Workshop in the MIDST of Protein-Protein Interaction Prediction

Sabanci University, Istanbul, Turkey

Wednesday, March 27, 2019


This one-day workshop was delivered by Professor Özlem Keskin from Koç University. The morning session was devoted to the theory about the protein protein interactions. In the afternoon, hands-on sessions was carried out. Protein-protein interaction (PPI) prediction is directly related to an in depth understanding of many biological processes. The morning session of this event covers theoretical information on the importance of PPIs, details about their role on binding, signaling, regulation as well the effect of mutations on these mechanisms. Since experimental procedures are expensive and hard to apply on a large scale, computational approaches have become important in detecting PPIs in large amounts of sequence and structural data. Thus, the approaches towards predicting PPIs with computational tools will be explained. The afternoon will be devoted to a hands-on session on a template-based protein-protein interaction tool, Protein Interactions by Structural Matching (PRISM)